Use of the Proteonano™ Platform for Robust and Fast Large cohort Proteomic Studies
Based on the high-throughput ultraplex proteomics platform Proteonano™, we aim to achieve rapid and robust workflow for large-cohort proteomics studies.
In large cohort proteomics experiments with mass spec, subgroups of protein measurements with quantitatively different behaviors (i.e. batch effect) oftentimes hinders the downstream bioinformatic analysis. To address this issue, Nanomics’ s Proteonano™ Ultraplex proteomics platform features a built-in quality control system (QCS), enabling
comprehensive monitoring at the individual sample level. Here’s how it works:
Proteonano™ quality control system (QCS)
Incubation controls:
For a standard 96-well plate experiment, we recommend using six quality control (QC) samples to monitor the entire platform’s workflow, as shown in Figure 3.
Detection controls:
LC-MS/MS status check prior experiments
Detection controls:
LC-MS/MS status check prior experiments
